基本情况

姓名:谭彩萍

性别:女

出生年月:1981-03

籍贯:湖南省常德市

职位:

副教授,博士生导师

联系方式

电话:+86-20-84113780 (O),13632401465 (M)

传真:暂未填写

邮箱:tancaip@mail.sysu.edu.cn

通讯地址:广东省广州市新港西路135号威尼斯官网化学与化学工程学会

邮编:510275

个人网站:暂未填写

教育经历

1998.09—2002.06? 华南师范大学化学与环境学会,学士;

2002.09—2008.06? 威尼斯官网化学与化学工程学会,博士。

工作经历

2008.03—2011.03? 威尼斯官网生命科学学会,博士后;?

2011.04—2016.01? 威尼斯官网化学与化学工程学会,讲师;

2016.02—2017-02? 美国芝加哥大学,访问学者;

2016.01—至今? ? 威尼斯官网化学与化学工程学会,副教授。

讲授课程

本科生课程《无机化学》、《化会员物学综合实验》、《现代无机化学进展》、《基础化学实验》、《普通化学》。

科研方向

? 从事的学科领域为生物无机化学。研究兴趣包括靶向性金属抗肿瘤药物的设计、抗肿瘤活性及机制研究。近两年,以与肿瘤发生、发展的关键的蛋白分子为靶点,设计了系列的金属配合物作为新颖的抑制剂,并研究了它们的抗肿瘤作用机制。主要研究的靶点包括组蛋白去乙酰化酶(Histone deacetylases, HDACs)和细胞周期素依赖性激酶(Cyclin-dependent kinases, CDKs)等。

科研项目

? ?1.?广东省自然科学基金(杰出青年基金),2015.08-2019.08,100?万元。

? ?2.?国家自然科学基金(面上项目),2018.01-2021.12,64.0?万元。

? ?3.?国家自然科学基金(面上项目),2016.01-2019.12,77.6?万元。?

? ?4.?广东省“百千万工程青年拔尖人才”,2016.08-2019.08,10?万元。?

? ?5.?高校基本科研业务费青年教师重点培育项目,2016.01-2017.12,30?万元。?

? ?6.?国家高技术研究发展计划(863计划)子课题,2012.01-2015.12,92.5?万元。?

? ?7.?国家自然科学基金?(青年科学基金项目),2013.01-2015.012,25?万元。?

? ?8.?广州市科技计划项目,2014.01-2016.12,8?万元。?

? ?9.?高校基本科研业务费青年教师培育项目,2013.01-2015.12,10?万元。

?10.?第四十四批中国博士后科学基金,2008.03-2010.03,3?万元。

获奖情况

暂无资料

论著一览

2017
? 1. Cao, J. J.,?Tan, C. P.*, Chen, M. H., Wu, N., Yao, D. Y., Liu, X. G., Ji, L.-N., Mao, Z. W.* Targeting cancer cell metabolism with mitochondria-immobilized phosphorescent cyclometalated iridium (III) complexes.?Chemical Science2017, 8, 631-640.?IF: 8.668

? 2. Chen, M. H., Wang, F. X., Cao, J. J.,?Tan, C. P.*, Ji, L. N. and Mao, Z. W.* Light-Up Mitophagy in Live Cells with Dual-Functional Theranostic Phosphorescent Iridium(III) Complexes.?ACS Applied Materials & Interfaces,?2017, 9 (15), 13304-13314.?IF: 7.504

? 3. Zhang, D. Y., Zheng, Y.,?Tan, C. P.*, Sun, J. H., Zhang, W.,?Ji, L. N. and Mao, Z. W.* Graphene Oxide Decorated with Ru(II)–Polyethylene Glycol Complex for Lysosome-Targeted Imaging and Photodynamic/Photothermal Therapy.?ACS Applied Materials & Interfaces2017, 9 (8), 6761-6771.?IF: 7.504

? 4. Wang, F. X., Chen, M. H., Lin, Y. N., Zhang, H.,?Tan, C. P.*, Ji, L. N. and Mao, Z. W.* Dual Functions of Cyclometalated Iridium(III) Complexes: Anti-Metastasis and Lysosome-Damaged Photodynamic Therapy.?ACS Applied Materials & Interfaces,?2017,?9?(49), 42471–42481.?IF: 7.504

? 5. Zhang, D. Y., Zheng, Y., Zhang, H., He, L.,?Tan, C. P.*, Sun, J. H., Zhang, W., Peng, X. Y., Ji, L. N. and Mao, Z. W.* Ruthenium complex-modified carbon nanodots for lysosome-targeted one- and two-photon imaging and photodynamic therapy.?Nanoscale, 2017,?9, 18966-18976.IF: 7.367

? 6. Xue, S. S.,?Tan, C. P.*, Chen, M. H., Cao, J. J., Zhang, D. Y., Ye, R. R., Ji, L. N. and Mao, Z. W.* Tumor-targeted supramolecular nanoparticles self-assembled from a ruthenium-beta-cyclodextrin complex and an adamantane-functionalized peptide.?Chemical Communications2017,?53 (5), 842-845.?IF: 6.319?(Front Cover)

? 7. Wu, N., Cao, J. J., Wu, X. W.,?Tan, C. P.*, Ji, L. N. and Mao, Z. W.* Iridium(III) Complexes with Five-Membered Heterocyclic Ligands for Combined Photodynamic Therapy and Photoactivated Chemotherapy.?Dalton Transactions2017,?46, 13482-13491.?IF: 4.029

? 8. Zheng, Y., He, L., Zhang, D. Y.,?Tan, C. P.*, Ji, L. N. and Mao, Z. W.* Mixed-ligand iridium(III) complexes as photodynamic anticancer agents.?Dalton Transactions2017, 46, 11395-11407.?IF: 4.029

? 9. Ye, R. R.,Cao, J. J.,?Tan, C. P.,Ji, L. N.,Mao, Z. W.*, Valproic Acid-Functionalized Cyclometalated Iridium(III)Complexes as Mitochondria-Targeting Anticancer Agents.?Chemistry-A European Journal2017,?23(60), 15166-15176.?IF: 5.317

2016
? 10. Wang, F. X., Chen, M. H., Hu, X. Y., Ye, R. R.,?Tan, C. P.*, Ji, L. N. and Mao, Z. W. Ester-Modified Cyclometalated Iridium(III) Complexes as Mitochondria-Targeting Anticancer Agents.?Scientific Reports2016, 6, 38954.?IF: 4.259

? 11. Ye, R. R.,?Tan, C. P.*, Ji, L. N. and Mao, Z. W.* Coumarin-appended phosphorescent cyclometalated iridium(III) complexes as mitochondria-targeted theranostic anticancer agents.?Dalton Transactions2016, 45(33), 13042-13051.?IF: 4.029?(Front Cover)

? 12. Ye, R. R.,?Tan, C. P.*, Chen, M. H., Hao, L., Ji, L. N. and Mao, Z. W.* Mono- and dinuclear phosphorescent rhenium(I) complexes: impact of subcellular localization on anticancer mechanisms.?Chemistry-A European Journal2016, 22(23), 7800-7809.?IF: 5.317

? 13. Zhang, W., Shen, J., Su, H., Mu, G., Sun, J. H.,?Tan, C. P., Liang, X. J., Ji, L. N., Mao, Z. W.* Co-delivery of cisplatin prodrug and chlorin e6 by mesoporous silica nanoparticles for chemo-photodynamic combination therapy to combat drug resistance.?ACS Applied Materials & Interfaces?2016, 8(21), 13332-13340.?IF: 7.504

2015
? 14. He, L., Li, Y.,?Tan, C. P.*, Ye, R. R., Chen, M. H., Cao, J. J., Ji, L. N. and Mao, Z. W.* Cyclometalated iridium(III) complexes as lysosome-targeted photodynamic anticancer and real-time tracking agents.?Chemical Science2015, 6, 5409-5418.?IF: 8.668?(Back Cover)

? 15. Ye, R. R.,?Tan, C. P.*, Lin, Y. N., Ji, L. N., Mao, Z. W.* A phosphorescent rhenium(I) histone deacetylase inhibitor: mitochondrial targeting and paraptosis induction.?Chemical Communications2015,?51(39),8353-8356.?IF: 6.319

? 16. Li, Y.,?Tan, C. P. (Co-first author), He, L., Ji, L. N., Mao, Z. W.* Phosphorescent iridium(III)-bis-N-heterocyclic carbene complexes as mitochondria-targeted theranostic and photodynamic anticancer agents.?Biomaterials2015, 39, 95-104.?IF: 8.402

? 17. Zhang, W., Li, Y., Sun, J. H.,?Tan, C. P., Ji, L. N., Mao, Z. W.* Supramolecular self-assembled nanoparticles for chemo-photodynamic dual therapy against cisplatin resistant cancer cells.?Chemical Communications2015, 51(10), 1807-1810.?IF: 6.319

? 18. Li, J. M., Zhang, W., Su, H., Wang, Y. Y.,?Tan, C. P., Ji, L. N., Mao, Z. W.* Reversal of multidrug resistance in MCF-7/ADR cells by codelivery of doxorubicin and BCL2 siRNA using a folic acid-conjugated polyethylenimine hydroxypropyl-beta-cyclodextrin nanocarrier.International Journal of Nanomedicine2015, 10, 3147-3162.?IF: 4.300

2014
? 19. He, L.,?Tan, C. P.*, Ye, R. R., Zhao, Y. Z., Liu, Y. H., Zhao, Q., Ji, L. N., Mao, Z. W.* Theranostic iridium(III) complexes as one- and two-photon phosphorescent trackers to monitor autophagic lysosomes.?Angewandte Chemie International Edition2014, 53(45), 12137-12141.IF: 11.994

? 20. Ye, R. R.,?Tan, C. P.*,?He, L., Chen, M. H., Ji, L. N., Mao, Z. W.* Cyclometalated Ir(III) complexes as targeted theranostic anticancer therapeutics: combining HDAC inhibition with photodynamic therapy.?Chemical Communications2014, 50(75), 10945-10948.?IF: 6.319

? 21. He, L., Liao, S. Y., Tan, C. P.*, Lu, Y. Y., Xu, C. X., Ji, L. N., Mao, Z. W.* Cyclometalated iridium(III)-beta-carboline complexes as potent autophagy-inducing agents.?Chemical Communications2014, 50(42), 5611-5614.?IF: 6.319

? 22.?Tan, C. P., Lu, Y. Y., Ji, L. N., Mao, Z. W.* Metallomics insights into the programmed cell death induced by metal-based anticancer compounds.?Metallomics?2014, 6(5), 978-995.?IF: 3.975?(Front Cover)

? 23. Zhao, M. X., Zhao, M., Zeng, E. Z., Li, Y., Li, J. M., Cao, Q.,?Tan, C. P.,?Ji, L. N., Mao, Z. W.* Enhanced anti-cancer efficacy to cancer cells by doxorubicin loaded water-soluble amino acid-modified beta-cyclodextrin platinum complexes.?Journal of Inorganic Biochemistry2014, 137, 31-39.?IF: 3.348

? 24. Li, Y., Liu, G. F.*,?Tan, C. P.,?Ji, L. N., Mao, Z. W.* Antitumor properties and mechanisms of mitochondria-targeted Ag(I) and Au(I) complexes containing N-heterocyclic carbenes derived from cyclophanes.?Metallomics?2014, 6(8), 1460-1468.?IF: 3.975

2013
? 25. Ye, R. R., Ke, Z. F.,?Tan, C. P.*, He, L., Ji, L. N., Mao, Z. W.* Histone-deacetylase-targeted fluorescent ruthenium(II) polypyridyl complexes as potent anticancer agents.?Chemistry-A European Journal?2013, 19(31), 10160-10169.?IF: 5.317?(Front Cover)

? 26. He, L., Liao, S. Y.,?Tan, C. P.*, Ye, R. R., Xu, Y. W., Zhao, M., Ji, L. N., Mao, Z. W.* Ruthenium-arene-carboline complexes as potent inhibitors of cyclin-dependent kinase 1: synthesis, characterization and anticancer mechanism studies.?Chemistry-A European Journal?2013, 19(36), 12152-12160.?IF: 5.317

2012
? 27. Zheng, X. H., Zhong, Y. F.,?Tan, C. P., Ji, L. N., Mao, Z. W.* Pt(II) squares as selective and effective human telomeric G-quadruplex binders and potential cancer therapeutics.?Dalton Transactions2012,?41(38), 11807-11812.?IF: 4.177

? 28. Wang, H. L., De Yonker, N. J., Gao, H.,?Tan, C. P., Zhang, X. T., Ji, L. N., Zhao, C. Y.*, Mao, Z. W.* Aquation and dimerization of osmium(II) anticancer complexes: a density functional theory study.?Rsc Advances2012, 2(2), 436-446.?IF: 3.289

? 29. Li, J. M., Wang, Y. Y., Zhao, M. X.,?Tan, C. P., Li, Y. Q., Le, X. Y., Ji, L. N., Mao, Z. W.* Multifunctional QD-based co-delivery of siRNA and doxorubicin to HeLa cells for reversal of multidrug resistance and real-time tracking.?Biomaterials?2012,?33(9), 2780-2790.?IF: 8.387

2011
? 30.?Tan, C. P., Wu, S. H., Lai, S. S., Wang, M. X., Chen, Y., Zhou, L. J., Zhu, Y. P., Lian, W., Peng, W. L., Ji, L. N., Xu, A. L.* Synthesis, structures, cellular uptake and apoptosis-inducing properties of highly cytotoxic ruthenium-Norharman complexes.?Dalton Transactions2011,40(34), 8611-8621.?IF: 4.029

? 31.?Tan, C. P., Hu, S., Liu, J.*, Ji, L. N.* Synthesis, characterization, antiproliferative and anti-metastatic properties of two ruthenium-DMSO complexes containing 2,2'-biimidazole.?European Journal of Medicinal Chemistry2011, 46(5), 1555-1563.?IF: 4.519

? 32. Zhao, M. X., Li, J. M., Du, L. Y.,?Tan, C. P., Xia, Q.*, Mao, Z. W.*, Ji, L. N. Targeted cellular uptake and sirna silencing by quantum-dot nanoparticles coated with beta-cyclodextrin coupled to amino acids.?Chemistry-A European Journal?2011, 17(18), 5171-5179.?IF: 5.317

? 33. Li, J. M., Zhao, M. X., Su, H., Wang, Y. Y.,?Tan, C. P., Ji, L. N., Mao, Z. W.* Multifunctional quantum-dot-based siRNA delivery for HPV18 E6 gene silence and intracellular imaging.?Biomaterials?2011, 32(31), 7978-7987.?IF: 8.402

2003-2010
? 34.?Tan, C. P.,?Lai, S. S., Wu, S. H., Hu, S., Zhou, L. J., Chen, Y., Wang, M. X., Zhu, Y. P., Lian, W., Peng, W. L., Ji, L. N., Xu, A. L.* Nuclear permeable ruthenium(II) beta-carboline complexes induce autophagy to antagonize mitochondrial-mediated apoptosis.?Journal of Medicinal Chemistry?2010, 53(21), 7613-7624.?IF: 6.259

? 35.?Tan, C. P., Liu, J.*, Li, H., Zheng, W. J., Shi, S., Chen, L. M., Ji, L. N.* Differences in structure, physiological stability, electrochemistry, cytotoxicity, DNA and protein binding properties between two Ru(III) complexes.?Journal of Inorganic Biochemistry?2008,?102(2), 347-358.IF: 3.348

? 36.?Tan, C. P., Liu, J.*, Chen, L. M., Shi, S., Ji, L. N.* Synthesis, structural characteristics, DNA binding properties and cytotoxicity studies of a series of Ru(III) complexes.?Journal of Inorganic Biochemistry2008, 102(8), 1644-1653.?IF: 3.348

? 37. Liu, Y. N., Shi, S., Mei, W. J.,?Tan, C. P., Chen, L. M., Liu, J.*, Zheng, W. J.*, Ji, L. N. In vitro and in vivo investigations on the antiviral activity of a series of mixed-valence rare earth borotungstate heteropoly blues.?European Journal of Medicinal Chemistry2008, 43(9), 1963-1970.?IF: 3.348

? 38. Liu, J.*, Zheng, W. J.*, Shi, S.,?Tan, C. P., Chen, J. C., Zheng, K. C., Ji, L. N. Synthesis, antitumor activity and structure-activity relationships of a series of Ru(II) complexes.?Journal of Inorganic Biochemistry2008, 102(2), 193-202.?IF: 3.348

? 39. Chen, L. M., Liu, J.*, Chen, J. C.,?Tan, C. P., Shi, S., Zheng, K. C., Ji, L. N.* Synthesis, characterization, DNA-binding and spectral properties of complexes [Ru(L)(4)(dppz)](2+) (L = Im and MeIm).?Journal of Inorganic Biochemistry?2008, 102(2), 330-341.?IF: 3.348

? 40. Chen, L. M., Liu, J.*, Chen, J. C., Shi, S.,?Tan, C. P., Zheng, K. C., Ji, L. N.* Experimental and theoretical studies on the DNA-binding and spectral properties of water-soluble complex [Ru(MeIm)(4)(dpq)](2+).?Journal of Molecular Structure?2008, 881(1-3), 156-166.?IF: 1.753

? 41. Shi, S., Liu, J.*, Li, J., Zheng, K. C., Huang, X. M.,?Tan, C. P., Chen, L. M., Ji, L. N.* Synthesis, characterization and DNA-binding of novel chiral complexes Delta- and Lambda-[Ru(bpy)(2)L](2+) (L = o-mopip and p-mopip).?Journal of Inorganic Biochemistry2006, 100(3), 385-395.?IF: 3.348

? 42. Shi, S., Liu, J.*, Li, J., Zheng, K. C.,?Tan, C. P., Chen, L. M., Ji, L. N.* Electronic effect of different positions of the -NO2 group on the DNA-intercalator of chiral complexes [Ru(bpy)(2)L](2+) (L = o-npip, m-npip and p-npip).?Dalton Transactions2005, 11), 2038-2046.?IF: 4.029

? ?43. Liu, J.*, Mei, W. J., Xu, A. W.,?Tan, C. P., Shi, S., Ji, L. N. Synthesis, characterization and antiviral activity against influenza virus of a series of novel manganese-substituted rare earth borotungstates heteropolyoxometalates.?Antiviral Research?2004, 62(1), 65-71.?IF: 4.271

? ?44. Liu, J.*, Mei, W. J., Xu, A. W.,?Tan, C. P., Ji, L. N. Synthesis, characterization and antiviral activity of nickel-substituted rare earth molybdosilicic heteropoly blues.?Transition Metal Chemistry?2003, 28(5), 500-505.?IF: 1.358

相关成果

暂无资料